Archive for June, 2006

WHOLE BODY DETOXIFICATION

Whole body detoxification has fans, but most medical experts say the only thing cleaned out is bank accounts

Don’t be surprised if a clean-living friend tells you they’re going through `detox.’Odds are they’re not talking about treatment for alcohol or drug addiction.Nor are they referring to the term’s other definitions – the elimination of waste products from blood through dialysis, or the elimination of excess metals through chelation therapy. The word detox, short for detoxification, has expanded to include the removal of toxins, often of an undefined nature, from the entire body. The theory is, the body’s cleaning system, which includes the liver, kidney, lungs, gastrointestinal tract and skin, needs help removing an ever-increasing onslaught of toxins, or poisons.The list of toxins that detox advocates condemn is long and includes contaminants in the air, water and food supply. They may come from junk food, nicotine, alcohol, caffeine, over-the-counter medicines or dental fillings.

Marketing opportunity:Where there’s a health trend, there’s a marketing opportunity. A plethora of new books, Web sites, and ads advocate programs and products for eliminating toxins through – deep breath, please – specific diets and exercise routines, herbs, teas, oxygenated water, hydrotherapy, electromagnetic therapy, enemas, gall bladder flushes, clay baths and fasting. Plug in the word detox at www.amazon.com, and hundreds of selections pop up.The recommendations from some detox programs, such as eating fresh, whole foods and drinking plenty of water, are sound and could benefit health, medical professionals say”That’s just common sense,” said Dr. Philip Wood, a genetics professor and senior scientist at the Clinical Nutrition Research Center at UAB.Other recommendations, such ingesting dandelion root and milk thistle to cleanse your liver, or wearing foot pads treated with wood vinegar, bamboo sap and tourmaline to extract toxins, raise the `snake oil’ radar of mainstream medical professionals, who say the only thing these programs are guaranteed to decrease is your bank account.”There’s no scientific evidence that taking colonics and fruit flushes or any of that stuff is helpful,” said Dr. Michael Turner, an internal medicine physician in Calera. On second thought, “It’s helpful for the people selling it.”The British nonprofit group Sense about Science, which promotes the benefits of scientific research, recently denounced detox products in a report that states: “They waste money and sow confusion about how our bodies, nutrition and chemistry actually work.”Practitioners at the Center for Mind Body Medicine at Spa Moksha off U.S. 280 say their detox treatments, including herbalized steam treatments, oil enemas and therapeutic vomiting, work because they’re individualized treatments based on Ayurvedic medicine, which originated more than 5,000 years ago in India and is recognized by the World Health Organization.
Everyone is different:”You have to be careful,” said Ayurvedic practitioner Drew Reardon. “Everyone is different.”Dr. Elson Haas, a San Rafael, Calif., physician whose most recent book is “The New Detox Diet,” said he became a detox believer in 1975, when he embarked on a 10-day “juice cleanse.” His health improved so dramatically that he repeats the cleanse every spring, he says.

Detox doesn’t have to mean a fast, though, Haas said, during a phone interview from his office. It can mean eating natural foods and getting more sleep, or getting rid of habits such as caffeine or nicotine.
Programs aimed at detoxing from any and all toxins are “nebulous,” UAB’s Wood said. They differ dramatically from treatments to detox from a single substance, such as alcohol.
“That’s a true detox,” he said. “There’s a clear way to evaluate it.”
For would-be detoxers, Wood suggests they ask the following questions – all of which are difficult to find answers to:

How do you know what to ingest to clear the presumed toxins?

What are the detox levels for these toxins, and how do you know when you’re detoxed?

How do you avoid becoming intoxicated by the detox treatment?

The bottom line, mainstream medical professionals say, is that your body was designed to purify itself and usually will do that if you take care of it.
“A healthy diet with fruits and vegetables and lean meats and low in saturated fat definitely will promote health,” said Susan Stone, a registered dietitian at St. Vincent’s Wellness Services. “That’s what you need to do rather than relying on a detox diet.”

KATHY SEALE
News staff writer The Birmingham News E-mail: kseale@bhamnews.com

Comments

Chelation Therapy

Chelation Therapy

Definition

In chelation therapy, chemical solutions are used in an attempt to prevent or reverse cardiovascular problems. By binding tightly to calcium and other minerals, chelating agents are thought to remove such substances from atherosclerotic plaques.

Description

Thousands of Americans have received chelation therapy, and many others are wondering whether this treatment can truly reverse the atherosclerosis that obstructs the blood flow in their arteries. The complications of atherosclerosis depend on which blood vessels are affected. For example, plaques that form in the coronary arteries can cause heart attacks or angina, while obstructions in the blood vessels that nourish the brain can cause stroke. Claudication, blockage in arteries that feed the lower part of the body, can cause pain in the legs. Chelation’s proponents say that it is safer and more effective than the surgical procedures that are sometimes used to remove the atherosclerotic blockages or reroute blood flow around them. However, chelation therapy is not covered by most third-party payers because the mainstream of medicine believes that this treatment can be risky and offers no benefits. The word chelation comes form the Greek root chele which means “claw.” The original concept of using chelation therapy in patients with atherosclerosis is startling in its simplicity. The chelating agent used most often for treating atherosclerosis is ethylenediamine tetraacetate – EDTA for short – which was developed in Germany during the 1930s for use in the dye industry. EDTA attaches tightly to several metals, including iron, mercury, copper, lead, zinc, aluminum, and calcium. Soon, medical researchers began to use EDTA to remove these metals from biologic systems, including the human body, in cases of poisoning or exposure to toxins. Over the next two decades, EDTA became the treatment of choice for lead or arsenic poisoning, and today treatment of lead poisoning remains the only use of EDTA that has been approved by the Food and Drug Administration. After EDTA has captured the minerals, the kidneys remove both the chelator and the metal bound to it from the body. Since chelation therapy is approved for the treatment of lead poisoning, it can be legally prescribed and performed. Both the critics and the proponents of chelation therapy have consistently called for randomized, “double-blind” trials. A small research study along these lines was reported in 1994. In this study, a number of patients were recruited from clinics specializing in atherosclerosis in the arteries to the legs. The patients were then randomly assigned to receive infusions with chelating agents or an inactive saline (salt water) solution. The infusions were indistinguishable by container, labeling, or color. Each patient received a total of 20 infusions given over about three hours, twice per week for 10 weeks. At the end of the study period, there was a significant improvement in the distance the patients could walk in both groups. However, there was no difference between the patients who had received chelation therapy and those who had received saline in terms of the distance they could walk without symptoms. Chelation therapy also did not have any detectable benefit on fatigue, mood, or general quality of life. The safety of chelation therapy has sometimes been questioned, and it should be noted that there were no significant side effects in either group. This study does not put the chelation therapy controversy to rest. The number of patients in the study was small and the subjects were studied for only three months. The study did not, however, prove that chelation therapy is worthless and did not indicate that it is dangerous. Yet it did not show the types of dramatic benefits that are sometimes cited by chelation’s proponents. Pending further data, chelation therapy remains of unproven benefit.

Questions

Would chelation therapy help my atherosclerosis? What are the risks of chelation therapy? What are the treatment alternatives? What other medications are available and effective?

Comments

Chelation Therapy

Chelation Therapy
Before engaging in any complementary medical technique, you should be aware that many of these techniques have not been evaluated in scientific studies. Often, only limited information is available about their safety and effectiveness. Each state and each discipline has its own rules about whether practitioners are required to be professionally licensed. If you plan to visit a practitioner, it is recommended that you choose one who is licensed by a recognized national organization and who abides by the organization’s standards. It is always best to speak with your primary health care provider before starting any new therapeutic technique.

Background
Chelation therapy was developed during the 1950s as a way to cleanse the blood and blood vessel walls of toxins and minerals. Therapy involves infusions into the bloodstream of the chemical edetic acid (EDTA). Sometimes the therapy may be given by mouth, which occasionally uses other chemicals.
Chelation was initially used as a treatment for heavy metal poisoning, but some observers believed that people receiving chelation therapy were benefiting in other ways. In modern times, chelation practitioners may recommend this therapy for atherosclerosis (clogged arteries), heart disease, peripheral vascular disease (claudication), diabetes and many other health problems. Chelation practitioners often recommend 20 or more treatments, which may cost several thousand dollars.
The term “chelation” is also sometimes used in medicine as a general term to refer to the use of chemicals in the blood to remove specific toxins or contaminants (for example, deferoxamine is a chelating agent used to treat excessive amounts of iron in the body). This type of chelation should not be confused with EDTA chelation therapy.

Theory
It has been suggested that chelation breaks down cholesterol plaques that cause clogged arteries and removes calcium from these plaques. However, no convincing scientific evidence has supported this theory. Chelation has also been suggested as an antioxidant therapy, although there is limited research in this area as well.

Evidence
Scientists have studied chelation therapy for the following health problems:
Lead toxicity and heavy metal poisoning
Chelation therapy with calcium disodium EDTA is an accepted therapy in medical institutions for lead toxicity. Studies have demonstrated that chelation therapy reduced lead levels in the body and slowed progression of kidney failure in people with lead toxicity. Chelation therapy may also be used when toxic levels of iron, arsenic, or mercury are present.
Atherosclerosis
Several recent high-quality studies suggest that chelation does not improve atherosclerosis (clogged arteries). The American Heart Association does not recommend chelation therapy for arteriosclerotic heart disease. People with heart conditions should be evaluated by a qualified health care professional. Patients are advised not to delay starting more proven treatments to try chelation. Research is ongoing.
Improved kidney (renal) function
Repeated chelation therapy may improve renal function and slow the progression of renal insufficiency. Further research is needed to confirm these results.
Peripheral vascular disease
Studies suggest that chelation does not improve peripheral vascular disease, or claudication (exercise-induced pain or fatigue in the legs caused by clogged arteries).
Unproven Uses
Chelation therapy has been suggested for many other uses, based on tradition or on scientific theories. However, these uses have not been thoroughly studied in humans, and there is limited scientific evidence about safety or effectiveness. Some of these suggested uses are for conditions that are potentially life-threatening. Consult with a health care provider before using chelation for any use.
Abnormal heart rhythms
Alzheimer’s disease
Anemia
Arthritis
Band keratopathy (calcium deposition in the cornea)
Blood disorders
Cataracts
Chronic degenerative diseases
Chronic obstructive pulmonary disease
Coronary heart disease
Dementia
Diabetes
Digoxin toxicity
Disease diagnosis
Emphysema
Gallstones
Gout
Heart disease
Hemochromatosis
High blood pressure
Kidney diseases
Lupus
Macular degeneration
Memory problems
Neurodegenerative disorders
Osteoarthritis
Osteoporosis
Parkinson’s disease
Rheumatoid arthritis
Scleroderma
Sexual development
Sickle cell disease
Snake venom poisoning
Stroke
Thalassemia
Vision problems
Wilson’s disease
Potential Dangers
Chelation may cause many severe side effects, including severe kidney damage, reduction of the body’s ability to make new blood cells in the bone marrow, dangerously low blood pressure, fast heart rate, dangerously low calcium levels in the blood, increased risk of bleeding or blood clots (including interference with the effects of the blood-thinning drug warfarin [Coumadin]), immune reactions, abnormal heart rhythms, allergic reactions, blood sugar imbalances and convulsions. There have been reports of headache, fatigue, fever, nausea, vomiting, gastrointestinal upset, excessive thirst, sweating (diaphoresis), low white blood cell counts and low levels of blood platelets. People using chelation have had severe reactions in which they have stopped breathing. Death has been reported, although it is not clear if chelation therapy was the direct cause.
Avoid chelation therapy if you have heart, kidney or liver disease or any condition affecting blood cells or the immune system. Chelation should be avoided in pregnant or breast-feeding women and in children. Chelation may not be safe in anybody; speak with a qualified health provider to balance the risks and possible benefits.

Summary
Chelation therapy with EDTA has been suggested for many conditions. Chelation may play a role in the treatment of lead or heavy metal toxicity. It should be used only under the direct supervision of a qualified health care provider. Chelation has not been shown to be effective for any other condition. Recent studies suggest that chelation may not be beneficial as a treatment for clogged arteries or peripheral vascular disease. Chelation may cause many adverse effects or death. It should be avoided by patients with heart, kidney or liver disease; patients with conditions affecting blood cells or the immune system; pregnant or breast-feeding women; and children. Speak with your health care provider if you are considering chelation therapy.

The information in this monograph was prepared by the professional staff at Natural Standard, based on thorough systematic review of scientific evidence. The material was reviewed by the Faculty of the Harvard Medical School with final editing approved by Natural Standard.

Resources
  1. Natural Standard: An organization that produces scientifically based reviews of complementary and alternative medicine (CAM) topics
  2. National Center for Complementary and Alternative Medicine (NCCAM): A division of the U.S. Department of Health & Human Services dedicated to research
Selected Scientific Studies: Chelation Therapy
Natural Standard reviewed more than 10,300 articles to prepare the professional monograph from which this version was created.
Selected studies are listed below:
  1. Anderson TJ, Hubacek J, Wyse DG, et al. Effect of chelation therapy on endothelial function in patients with coronary artery disease: PATCH substudy. J Am Coll Cardiol 2003;41(3):420-425.
  2. Bell SA. Chelation therapy for patients with ischemic heart disease [Comment]. JAMA 2002;287(16):2077.
  3. Chappell LT, Miranda R, Hancke C, et al. EDTA chelation treatment for peripheral vascular disease. J Intern Med 1995;237(4):429-432.
  4. Chappell LT, Stahl JP, Evans R. EDTA chelation therapy for vascular disease: a meta-analysis using unpublished data. J Adv Med 1994;7:131-142.
  5. Chappell LT, Stahl JP. The correlation between EDTA chelation therapy and improvement in cardiovascular function: a meta-analysis. J Adv Med 1993;6:139-160.
  6. Chappell LT. Applications of EDTA chelation therapy. Alt Med Rev 1997;2(6):426-432.
  7. Ernst E. Chelation therapy for coronary heart disease: an overview of all clinical investigations. Am Heart J 2000;140(1):139-141.
  8. Ernst E. Chelation therapy for peripheral arterial occlusive disease: a systematic review. Circulation 1997;96(3):1031-1033.
  9. Grawehr M, Sener B, Waltimo T, Zehnder M. Interactions of ethylenediamine tetraacetic acid with sodium hypochlorite in aqueous solutions. Int Endod J 2003;36(6):411-417.
  10. Grebe HB, Gregory PJ. Inhibition of warfarin anticoagulation associated with chelation therapy. Pharmacotherapy 2002;22(8):1067-1069.
  11. Hellmich HL, Frederickson CJ, DeWitt DS, et al. Protective effects of zinc chelation in traumatic brain injury correlate with upregulation of neuroprotective genes in rat brain. Neurosci Lett 2004;355(3):221-225.
  12. Huynh-Do U. [Gout nephropathy—ghost or reality?]. Ther Umsch 2004;61(9):567-569.
  13. Knudtson ML, Wyse DG, Galbraith PD, et al. Chelation therapy for ischemic heart disease: a randomized controlled trial. JAMA 2002;287(4):481-486.
  14. Lin JL, Lin-Tan DT, Hsu KH, Yu CC. Environmental lead exposure and progression of chronic renal diseases in patients without diabetes. N Engl J Med 2003;348(4):277-286.
  15. Lin JL, Ho HH, Yu CC. Chelation therapy for patients with elevated body lead burden and progressive renal insufficiency: a randomized, controlled trial. Ann Intern Med 1999;130(1):7-13.
  16. Lyngdorf P, Guldager B, Holm J, et al. Chelation therapy for intermittent claudication: a double-blind, randomized, controlled trial. Circulation 1996;93(2):395-396.
  17. Markowitz ME. Managing childhood lead poisoning. Salud Publica Mex 2003;S225-S231.
  18. Morgan BW, Kori S, Thomas JD. Adverse effects in 5 patients receiving EDTA at an outpatient chelation clinic. Vet Hum Toxicol 2002;44(5):274-276.
  19. Najjar DM, Cohen EJ, Rapuano CJ, et al. EDTA chelation for calcific band keratopathy: results and long-term follow-up. Am J Ophthalmol 2004;137(6):1056-1064.
  20. Quan H, Ghali WA, Verhoef MJ, et al. Use of chelation therapy after coronary angiography. Am J Med 2001;111(9):686-691.
  21. Sang Choe E, Warrier B, Soo Chun J, et al. EDTA-induced activation of Ca-regulated proteins in the vaginal mucosa 2004;68A(1):159-167.
  22. Shannon M. Severe lead poisoning in pregnancy. Ambul Pediatr 2003;3(1):37-39.
  23. Strassberg D. Chelation therapy for patients with ischemic heart disease [Comment]. JAMA 2002;287(16):2077.
  24. van Rij AM, Solomon C, Packer SG, et al. Chelation therapy for intermittent claudication: a double-blind, randomized, controlled trial. Circulation 1994;90(3):1194-1199.
  25. Villarruz MV, Dans A, Tan F. Chelation therapy for atherosclerotic cardiovascular disease (Cochrane Review). Cochrane Database Syst Rev 2002;(4):CD002785.

Comments

Chelation a Possible Cure for Autism

Written by geri
Thursday, 09 March 2006
Parents and caregivers are crediting the process of chelation with curing their son of autism. He went from not responding to his parents, and continually spinning himself in circles, to talking and responding like a normal child.
Chelation is a common treatment for lead poisoning that’s been around for decades. The idea was to eliminate the mercury in the boy’s body. NBC TV-11 in San Francisco reported :
Some parents say chelation is bringing about dramatic change… Josh Shoemaker, almost 4, is not his old self, his parents are happy to say. Angie Shoemaker, Josh’s mom, says, “It’s just not even comparable. He’s just not the same child.

Comments

Chelation Therapy

Chelation Therapy
Definition

In chelation therapy, chemical solutions are used in an attempt to prevent or reverse cardiovascular problems. By binding tightly to calcium and other minerals, chelating agents are thought to remove such substances from atherosclerotic plaques.

Description

Thousands of Americans have received chelation therapy, and many others are wondering whether this treatment can truly reverse the atherosclerosis that obstructs the blood flow in their arteries. The complications of atherosclerosis depend on which blood vessels are affected. For example, plaques that form in the coronary arteries can cause heart attacks or angina, while obstructions in the blood vessels that nourish the brain can cause stroke. Claudication, blockage in arteries that feed the lower part of the body, can cause pain in the legs. Chelation’s proponents say that it is safer and more effective than the surgical procedures that are sometimes used to remove the atherosclerotic blockages or reroute blood flow around them. However, chelation therapy is not covered by most third-party payers because the mainstream of medicine believes that this treatment can be risky and offers no benefits. The word chelation comes form the Greek root chele which means “claw.” The original concept of using chelation therapy in patients with atherosclerosis is startling in its simplicity. The chelating agent used most often for treating atherosclerosis is ethylenediamine tetraacetate – EDTA for short – which was developed in Germany during the 1930s for use in the dye industry. EDTA attaches tightly to several metals, including iron, mercury, copper, lead, zinc, aluminum, and calcium. Soon, medical researchers began to use EDTA to remove these metals from biologic systems, including the human body, in cases of poisoning or exposure to toxins. Over the next two decades, EDTA became the treatment of choice for lead or arsenic poisoning, and today treatment of lead poisoning remains the only use of EDTA that has been approved by the Food and Drug Administration. After EDTA has captured the minerals, the kidneys remove both the chelator and the metal bound to it from the body. Since chelation therapy is approved for the treatment of lead poisoning, it can be legally prescribed and performed. Both the critics and the proponents of chelation therapy have consistently called for randomized, “double-blind” trials. A small research study along these lines was reported in 1994. In this study, a number of patients were recruited from clinics specializing in atherosclerosis in the arteries to the legs. The patients were then randomly assigned to receive infusions with chelating agents or an inactive saline (salt water) solution. The infusions were indistinguishable by container, labeling, or color. Each patient received a total of 20 infusions given over about three hours, twice per week for 10 weeks. At the end of the study period, there was a significant improvement in the distance the patients could walk in both groups. However, there was no difference between the patients who had received chelation therapy and those who had received saline in terms of the distance they could walk without symptoms. Chelation therapy also did not have any detectable benefit on fatigue, mood, or general quality of life. The safety of chelation therapy has sometimes been questioned, and it should be noted that there were no significant side effects in either group. This study does not put the chelation therapy controversy to rest. The number of patients in the study was small and the subjects were studied for only three months. The study did not, however, prove that chelation therapy is worthless and did not indicate that it is dangerous. Yet it did not show the types of dramatic benefits that are sometimes cited by chelation’s proponents. Pending further data, chelation therapy remains of unproven benefit.

Questions

Would chelation therapy help my atherosclerosis? What are the risks of chelation therapy? What are the treatment alternatives? What other medications are available and effective?

Comments